What is Percocet? Percocet is the brand name for a painkiller that combines oxycodone and acetaminophen. It contains an opioid pain reliever (oxycodone) and a non-opioid pain reliever (acetaminophen). Oxycodone works in the brain to change how your body feels and responds to pain. Acetaminophen can also reduce a fever. According to Mayo Clinic, Oxycodone […]